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Anti-infectious and anti-inflammatory effects of peptide fragments sequentially derived from the antimicrobial peptide centrocin 1 isolated from the green sea urchin, Strongylocentrotus droebachiensis.

Submission history

AMB Express Efficacy and safety profile of the novel antimicrobial peptide PXL in a mouse model of infected burn wounds. Agents 45, — Boge, L. Lipid-based liquid crystals as carriers for antimicrobial peptides: phase behavior and antimicrobial effect. Langmuir 32, — Boman, H. Peptide antibiotics and their role in innate immunity. Braun, K. Membrane interactions of mesoporous silica nanoparticles as carriers of antimicrobial peptides. Colloid Interface Sci.

Bray, B. Large-scale manufacture of peptide therapeutics by chemical synthesis. Drug Discov. Briers, Y. Breaking barriers: expansion of the use of endolysins as novel antibacterials against Gram-negative bacteria.

eLife digest

Art is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa. Agents Chemother. Brinckerhoff, L. Cancer 83, — Brogden, K. Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria? Chennupati, S. Effects of an LLderived antimicrobial peptide in an animal model of biofilm Pseudomonas sinusitis.

Allergy 23, 46— Chertov, O.

Capillary Electrophoresis of Proteins and Peptides

Ciornei, C. Antimicrobial and chemoattractant activity, lipopolysaccharide neutralization, cytotoxicity, and inhibition by serum of analogs of human cathelicidin LL Clifton, L. Effect of divalent cation removal on the structure of gram-negative bacterial outer membrane models. Langmuir 31, — Czaplewski, L. Alternatives to antibiotics-a pipeline portfolio review.

Lancet Infect.

Peptide Mapping Information | Thermo Fisher Scientific - US

Overcoming barriers in Pseudomonas aeruginosa lung infections: engineered nanoparticles for local delivery of a cationic antimicrobial peptide. Colloids Surf. B Biointerf. Davidson, D. The cationic antimicrobial peptide LL modulates dendritic cell differentiation and dendritic cell-induced T cell polarization. Defraine, V. Efficacy of artilysin Art against resistant and persistent Acinetobacter baumannii. Dorschner, R.

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The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides. Cutaneous injury induces the release of cathelicidin anti-microbial peptides active against group A Streptococcus. Dryden, M.

Complicated skin and soft tissue infection. Ebenhan, T. Antimicrobial peptides: their role as infection-selective tracers for molecular imaging.

BioMed Res. Eckert, R. Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development. Edsfeldt, S. Epand, R. Diversity of antimicrobial peptides and their mechanisms of action. Acta , 11— Falagas, M. Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Toxicity of polymyxins: a systematic review of the evidence from old and recent studies.

Care R Fjell, C. Designing antimicrobial peptides: form follows function. Fox, J. Antimicrobial peptides stage a comeback. Giuliani, A. Antimicrobial peptides: an overview of a promising class of therapeutics. Goldman, M. Cell 88, — Treatment with LL is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial. Wound Repair Regen. Hancock, R. Peptide antibiotics. Lancet , — Cationic antimicrobial peptides: towards clinical applications.

Expert Opin. Drugs 9, — PubMed Abstract Google Scholar.

Linkers, resins, and general procedures for solid-phase peptide synthesis.

Modulating immunity as a therapy for bacterial infections. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. The role of cationic antimicrobial peptides in innate host defences. Trends Microbiol. Hassan, M. Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance. Hayashi, M. The effect of lubricin on the gliding resistance of mouse intrasynovial tendon. Hunter, H.

18F-labeling of peptides and proteins using the SiFA protocol, Part 2

Human lactoferricin is partially folded in aqueous solution and is better stabilized in a membrane mimetic solvent. Izquierdo-Barba, I.

Incorporation of antimicrobial compounds in mesoporous silica film monolith. Biomaterials 30, — Jenssen, H. Peptide antimicrobial agents.

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Kosikowska, P. Antimicrobial peptides AMPs as drug candidates: a patent review Lai, Y. AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense.